Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29526856 | 0.83 | ATM (0.51) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL1169875 | 0.83 | ATM (0.51) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL19303225 | 0.80 | ATM (0.57) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL6114924 | 0.80 | ATM (0.57) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL5659077 | 0.80 | ATM (0.57) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL5659090 | 0.80 | ATM (0.57) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL9569979 | 0.80 | ATM (0.57) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL8565810 | 0.80 | L3MBTL1 (0.57) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL3127741 | 0.78 | ATM (0.56) | ATML3MBTL1CYP1A2CYP2A6PDPK1 | |
| SCHEMBL27483098 | 0.78 | L3MBTL1 (0.56) | ATML3MBTL1CYP1A2CYP2A6PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038229-A | Heteroaryl compounds and methods of use thereof | SUNOVION PHARMACEUTICALS INC | 2013-04-10 | — | — | CN | disclosed |
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |