Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27483098 | 0.98 | L3MBTL1 (0.56) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL2908675 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| Hydrochloric Acid SCHEMBL9253127 | 0.82 | L3MBTL1 (0.50) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL27508296 | 0.80 | ATM (0.57) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL6114924 | 0.80 | ATM (0.57) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL19303225 | 0.80 | ATM (0.57) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL5659090 | 0.80 | ATM (0.57) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL5659077 | 0.80 | ATM (0.57) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL9569979 | 0.80 | ATM (0.57) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 | |
| SCHEMBL3127741 | 0.78 | ATM (0.56) | L3MBTL1ATMCYP1A2CYP2A6PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1535958-A | Alpha-substituted pyrimidine. thioalkyl and alkyl ether compound | �������Ŷ���Լ��������˾ | 2004-10-13 | — | — | CN | disclosed |
| CN-1183773-A | Alpha-substituted pyrimidine-thioalkyl and alkylether compounds | UPJOHN CO (US) | 1998-06-03 | — | — | CN | disclosed |
| EP-0824524-A1 | ALPHA-SUBSTITUTED PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS AS INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | PHARMACIA & UPJOHN COMPANY (US) | 1998-02-25 | — | — | EP | disclosed |