Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699242 | 0.87 | KDM4E (0.55) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL4907876 | 0.81 | SMN1; SMN2 (0.52) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL4906781 | 0.80 | SMN1; SMN2 (0.44) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL27685335 | 0.78 | KMT2A (0.46) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL27508375 | 0.77 | KDM4E (0.41) | KMT2ACYP2D6CYP2C19CYP1A2KDM4E | |
| SCHEMBL4908330 | 0.75 | KDM4E (0.68) | KMT2ACYP2D6LMNAKDM4EMAPT | |
| SCHEMBL27548146 | 0.74 | CYP1A2 (0.46) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL1573428 | 0.71 | APAF1 (0.42) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL10795101 | 0.70 | KMT2A (0.55) | KMT2ACYP2D6CYP2C19CYP1A2LMNA | |
| SCHEMBL697750 | 0.68 | POLB (0.36) | KMT2ACYP2D6CYP2C19CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1151789-C | Utilization of aryl (or heteroaryl) azolylcarbinol derivatives in prepn. of medicament for treating troubles mediated by excess of substance P | ��˹���IJ�ʿʵ���ҹɷ�����˾ | 2004-06-02 | — | — | CN | claimed |