Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574142 | 0.88 | SMN1; SMN2 (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1573270 | 0.87 | KMT2A (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1573396 | 0.85 | ITGB3 (0.37) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL1573149 | 0.82 | PTGES (0.40) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL696323 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL698574 | 0.82 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL698793 | 0.82 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTTDP1 | |
| SCHEMBL4014276 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AALDH1A1KCNH2FPR2 | |
| SCHEMBL697528 | 0.81 | IDH1 (0.34) | SMN1; SMN2KMT2AMEN1LMNATSHR | |
| SCHEMBL696322 | 0.81 | ALDH1A1 (0.38) | SMN1; SMN2KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | claimed |
| US-7547718-B2 | Substituted imidazoles | PFIZER LIMITED (GB) | 2009-06-16 | — | — | US | claimed |