Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.62 |
| ▸ | MAOB | P27338 | 6/20 | 0.62 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162855 | 1.00 | MAOA (0.62) | MAOAMAOBSPHK1GRM2MAPT | |
| SCHEMBL6545054 | 0.88 | CD274 (0.50) | MAOAMAOBMAPTGRM6KDM4E | |
| SCHEMBL8044343 | 0.88 | CD274 (0.50) | MAOAMAOBMAPTGRM6KDM4E | |
| SCHEMBL20745515 | 0.88 | CD274 (0.50) | MAOAMAOBMAPTGRM6KDM4E | |
| SCHEMBL9218563 | 0.88 | CD274 (0.50) | MAOAMAOBMAPTGRM6KDM4E | |
| SCHEMBL5067829 | 0.88 | CD274 (0.50) | MAOAMAOBMAPTGRM6KDM4E | |
| Hydrochloric Acid SCHEMBL2495103 | 0.86 | CD274 (0.49) | MAOAMAOBMAPTGRM6KDM4E | |
| SCHEMBL11147860 | 0.85 | SPHK1 (0.52) | MAOAMAOBSPHK1MAPTSIRT1 | |
| SCHEMBL7067401 | 0.84 | MAOB (0.64) | MAOAMAOBSPHK1SIRT1GRM6 | |
| SCHEMBL28218104 | 0.84 | MAOB (0.64) | MAOAMAOBSPHK1SIRT1GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1169810-C | Peptide nucleic acid derivatives, intermediate for preparing them and medicinal composition containing them | 中国人民解放军军事医学科学院毒物药 | 2004-10-06 | — | — | CN | disclosed |
| CN-1330073-A | Peptide nucleic acid derivatives, intermediate for preparing them and medicinal composition containing them | INST OIF TOXIC MEDICINES PLA S (CN) | 2002-01-09 | — | — | CN | disclosed |