Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.64 |
| ▸ | MAOA | P21397 | 12/20 | 0.64 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | GRM6 | O15303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218104 | 1.00 | MAOB (0.64) | MAOBMAOASPHK1SIRT1GRM6 | |
| Hydrochloric Acid SCHEMBL28218107 | 0.99 | MAOB (0.63) | MAOBMAOASPHK1SIRT1GRM6 | |
| SCHEMBL16764924 | 0.88 | MAOA (0.51) | MAOBMAOAGRM6 | |
| SCHEMBL14555989 | 0.88 | MAOA (0.51) | MAOBMAOAGRM6 | |
| SCHEMBL20745387 | 0.88 | MAOA (0.51) | MAOBMAOAGRM6 | |
| SCHEMBL23243788 | 0.88 | MAOA (0.51) | MAOBMAOAGRM6 | |
| SCHEMBL20745461 | 0.88 | MAOA (0.51) | MAOBMAOAGRM6 | |
| SCHEMBL11147860 | 0.84 | SPHK1 (0.52) | MAOBMAOASPHK1SIRT1GRM6 | |
| SCHEMBL1162855 | 0.84 | MAOA (0.62) | MAOBMAOASPHK1SIRT1GRM6 | |
| SCHEMBL27508562 | 0.84 | MAOA (0.62) | MAOBMAOASPHK1SIRT1GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |