Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271018 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL9944130 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL28588307 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MEN1KMT2AHTT | |
| SCHEMBL2659395 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL28256008 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL28375616 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL27455048 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL16451131 | 0.80 | ALDH1A1 (0.51) | ALDH1A1TDP1MEN1KMT2AHTT | |
| SCHEMBL28916197 | 0.79 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL29945744 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101337895-B | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH NEW TECHNOLOGY DEV CT | 2011-05-11 | — | — | CN | claimed |
| CN-101337895-A | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-101337892-A | Method for preparing 2-brom-5-nitrobenzotrifluoride | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-106316864-A | Preparation method of 4-methyl-3-trifluoromethyl phenylamine | 苏州天马精细化学品股份有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-101337895-B | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH NEW TECHNOLOGY DEV CT | 2011-05-11 | — | — | CN | disclosed |
| CN-101337895-A | Method for preparing 2,2'-di(trifluoromethyl)-4,4'-benzidine | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-101337892-A | Method for preparing 2-brom-5-nitrobenzotrifluoride | WUYI TIANDA PREC CHEMICAL HIGH (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-100427483-C | Anthranilic acid amide derivatives and their pharmaceutical use | NOVARTIS AG (CH) | 2008-10-22 | — | — | CN | disclosed |
| CN-101198607-A | Phenylacetamides suitable as protein kinase inhibitors | NOVARTIS AG (CH) | 2008-06-11 | — | — | CN | disclosed |
| CN-101045727-A | Inhibitors of tyrosine kinases | NOVARTIS AG (CH) | 2007-10-03 | — | — | CN | disclosed |
| CN-1324022-C | Tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2007-07-04 | — | — | CN | disclosed |
| CN-1279026-C | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2006-10-11 | — | — | CN | disclosed |
| CN-1720244-A | Anthranilic acid amide derivatives and their pharmaceutical use | NOVARTIS AG (CH) | 2006-01-11 | — | — | CN | disclosed |
| CN-1675195-A | Tyrosine kinase inhibitors | NOVARTIS AG (CH) | 2005-09-28 | — | — | CN | disclosed |
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1342149-A | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |