Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 15/20 | 0.64 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.64 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.64 |
| ▸ | MAPK13 | O15264 | 13/20 | 0.64 |
| ▸ | GCGR | P47871 | 13/20 | 0.64 |
| ▸ | MAPK12 | P53778 | 13/20 | 0.64 |
| ▸ | MAPK11 | Q15759 | 13/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
| ▸ | FRK | P42685 | 1/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971902 | 0.85 | MAPK14 (0.68) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL17002177 | 0.85 | MAPK14 (0.83) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL4553281 | 0.79 | ALOX5 (1.00) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL6465062 | 0.79 | ALOX5 (1.00) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL17002222 | 0.79 | MAPK14 (0.76) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL17002226 | 0.79 | MAPK14 (1.00) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL6003680 | 0.78 | MAPK14 (1.00) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL8792966 | 0.77 | MAPK14 (0.70) | MAPK14CSNK1DCSNK1EMAPK13GCGR | |
| SCHEMBL17002231 | 0.77 | MAPK14 (0.76) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 | |
| SCHEMBL18960509 | 0.76 | MAPK14 (0.83) | ALOX5MAPK14CSNK1DCSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1145623-C | Imidazole derivatives | - | 2004-04-14 | — | — | CN | claimed |
| CN-1145623-C | Imidazole derivatives | - | 2004-04-14 | — | — | CN | disclosed |