Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27493347 | 0.82 | CYP2D6 (0.41) | SMN1; SMN2MEN1KMT2AITGB3ITGAV | |
| SCHEMBL27494110 | 0.82 | CYP2D6 (0.41) | SMN1; SMN2MEN1KMT2AITGB3ITGAV | |
| SCHEMBL27511354 | 0.82 | CYP2D6 (0.41) | SMN1; SMN2MEN1KMT2AITGB3ITGAV | |
| SCHEMBL27509544 | 0.80 | ITGB3 (0.41) | RAB9ANPC1SMN1; SMN2ITGB3ITGAV | |
| SCHEMBL27524759 | 0.79 | ITGB3 (0.42) | ITGB3ITGAVITGA2BPOLB | |
| SCHEMBL27511699 | 0.78 | ITGB3 (0.52) | RAB9ANPC1SMN1; SMN2KMT2APKM | |
| SCHEMBL27494528 | 0.77 | ITGB3 (0.45) | MEN1KMT2APKMITGB3ITGAV | |
| SCHEMBL27492956 | 0.72 | DRD2 (0.42) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27495702 | 0.72 | DRD2 (0.42) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL27494111 | 0.72 | DRD2 (0.42) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1223650-A | Piperidines and pyrrolidines | MERCK PATENT GMBH (DE) | 1999-07-21 | — | — | CN | disclosed |