Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841947 | 0.82 | MAOA (0.56) | MAPTCA12CA9KDM4EMAOB | |
| SCHEMBL3914336 | 0.81 | MAOB (0.55) | KDM4EMAOBMAOAKMT2AALDH1A1 | |
| SCHEMBL8178252 | 0.81 | CA12 (0.51) | CA12CA9KDM4EMAOBMAOA | |
| SCHEMBL27511219 | 0.80 | FLT3 (0.47) | MAPTCA12CA9KDM4EMAOB | |
| Hydrochloric Acid SCHEMBL6983719 | 0.79 | FLT3 (0.46) | MAPTCA12CA9KDM4EMAOB | |
| SCHEMBL8142148 | 0.79 | TBXAS1 (0.46) | KDM4EMAOBMAOAALDH1A1HRH3 | |
| SCHEMBL3903384 | 0.79 | MAOB (0.57) | CA12CA9KDM4EMAOBALDH1A1 | |
| SCHEMBL7030964 | 0.78 | MAOB (0.50) | MAPTKDM4EMAOBKMT2AALDH1A1 | |
| SCHEMBL282766 | 0.78 | CA12 (0.49) | CA12CA9MAOBMAOAPOLB | |
| SCHEMBL5711170 | 0.78 | CA12 (0.54) | MAPTCA12CA9KDM4EMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1209060-A | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-02-24 | — | — | CN | disclosed |