Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8090741 | 0.86 | DPP4 (0.48) | ALDH1A1MAPK1SMN1; SMN2DPP4TDP1 | |
| SCHEMBL11216806 | 0.86 | DPP4 (0.54) | ALDH1A1MAPK1SMN1; SMN2DPP4TTR | |
| SCHEMBL27289072 | 0.85 | TSHR (0.45) | ALDH1A1MAPK1SMN1; SMN2TTRMEN1 | |
| SCHEMBL9685948 | 0.85 | CLCN2 (0.46) | ALDH1A1MAPK1SMN1; SMN2TTRMEN1 | |
| SCHEMBL7022036 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPK1SMN1; SMN2DPP4TDP1 | |
| SCHEMBL2430970 | 0.83 | CLCN2 (0.42) | ALDH1A1MAPK1SMN1; SMN2DPP4TTR | |
| SCHEMBL29570348 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPK1SMN1; SMN2DPP4TDP1 | |
| SCHEMBL935886 | 0.83 | CLCN2 (0.42) | ALDH1A1MAPK1SMN1; SMN2DPP4TDP1 | |
| SCHEMBL3392120 | 0.82 | TDP1 (0.48) | ALDH1A1MAPK1SMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL25200699 | 0.81 | METAP2 (0.47) | ALDH1A1MAPK1SMN1; SMN2DPP4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102365276-A | Substituted spiro-amide compounds | GRUENENTHAL GMBH | 2012-02-29 | — | — | CN | disclosed |
| CN-1240684-C | Dibenzocycloheptene compound | UBE INDUSTRIES (JP) | 2006-02-08 | — | — | CN | disclosed |
| CN-1531528-A | Dibenzocycloheptene compound | ��˲���ʽ���� | 2004-09-22 | — | — | CN | disclosed |