Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 8/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL23360905 | 0.97 | — | — | |
| SCHEMBL1398156 | 0.87 | GSK3A (0.46) | MAP3K14CRBNCYP19A1IDO1GLA | |
| SCHEMBL19370773 | 0.74 | — | — | |
| SCHEMBL3578552 | 0.74 | — | — | |
| SCHEMBL2174994 | 0.71 | — | — | |
| SCHEMBL5909391 | 0.71 | MAP3K14 (0.55) | MAP3K14CRBNCYP19A1IDO1LMNA | |
| SCHEMBL6897659 | 0.69 | — | — | |
| SCHEMBL10573688 | 0.69 | — | — | |
| SCHEMBL17114323 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435439-A | Preparation method of bromomethyl cyclobutane | HONGSHENG SCI TECH DEV CO LTD | 2013-12-11 | — | — | CN | disclosed |
| CN-1268593-C | Method for isomerizating 1,4-dichloro-2-butylenes from syn form to anti form | UNIV ZHEJIANG (CN) | 2006-08-09 | — | — | CN | disclosed |
| CN-1660729-A | Method for isomerizating 1,4-dichloro-2-butylenes from syn form to anti form | UNIV ZHEJIANG (CN) | 2005-08-31 | — | — | CN | disclosed |