Trans-Asarone

Trans-Asarone

SCHEMBL27514432

CC=Cc1cc(OC)c(OC)cc1OC.CCC(=O)OC(=O)CC.[NaH]

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.66
CYP3A4 P08684 1/20 0.66
NFE2L2 Q16236 1/20 0.54
ABCG2 Q9UNQ0 1/20 0.49
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CYP1A1 P04798 2/20 0.41
CYP1B1 Q16678 2/20 0.41
CYP1A2 P05177 1/20 0.41
SNCA P37840 2/20 0.41
APP P05067 1/20 0.41
POLB P06746 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB2 P47870 1/20 0.40
VCP P55072 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trans-Asarone SCHEMBL30487992 0.82 CYP3A4 (0.78) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Trans-Asarone SCHEMBL940800 0.81 HMGCR (1.00) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Cis-Asarone SCHEMBL29655982 0.81 HMGCR (1.00) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Trans-Asarone SCHEMBL528746 0.81 HMGCR (1.00) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Trans-Asarone SCHEMBL29433647 0.81 HMGCR (1.00) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Cis-Asarone SCHEMBL528747 0.81 HMGCR (1.00) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Trans-Asarone SCHEMBL29268894 0.79 HMGCR (0.95) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
SCHEMBL19342857 0.77 GABRA1 (0.57) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
Trans-Asarone SCHEMBL30487993 0.73 HMGCR (0.57) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1
SCHEMBL14875237 0.71 NFE2L2 (0.73) HMGCRCYP3A4NFE2L2ABCG2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1234672-C Process for producing alpha-asarone raw material LIU BOCHUN (CN) 2006-01-04 CN disclosed
CN-1511817-A Process for producing alpha-asarone raw material 刘博纯 2004-07-14 CN disclosed