Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 7/20 | 0.47 |
| ▸ | PPIA | P62937 | 6/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27547572 | 0.84 | CYP2C9 (0.42) | C5AR1PPIAMEN1KMT2AKDM4E | |
| SCHEMBL27515135 | 0.82 | C5AR1 (0.53) | C5AR1 | |
| SCHEMBL6675020 | 0.79 | C5AR1 (0.46) | C5AR1CYP19A1ACP1PTPN12PTPN13 | |
| SCHEMBL6675023 | 0.79 | C5AR1 (0.58) | C5AR1MEN1KMT2A | |
| SCHEMBL6686056 | 0.78 | C5AR1 (0.54) | C5AR1MEN1KMT2A | |
| SCHEMBL6686052 | 0.78 | C5AR1 (0.43) | C5AR1PPIAMEN1KMT2ACYP19A1 | |
| SCHEMBL27479892 | 0.77 | PTGER1 (0.42) | C5AR1PPIAP2RX4MEN1KMT2A | |
| SCHEMBL27532762 | 0.73 | CYP19A1 (0.48) | C5AR1CYP19A1 | |
| SCHEMBL448037 | 0.71 | RXRA (0.55) | — | |
| SCHEMBL6678137 | 0.71 | C5AR1 (0.46) | C5AR1P2RX4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1172473-A | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |