Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 9/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.39 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678649 | 0.85 | CTSV (0.41) | C5AR1PPIAMEN1MAPTKMT2A | |
| SCHEMBL6675020 | 0.83 | C5AR1 (0.46) | C5AR1MAPTCYP19A1ACP1PTPN12 | |
| SCHEMBL6678420 | 0.82 | PPIA (0.44) | C5AR1PPIAMEN1MAPTKMT2A | |
| SCHEMBL6679217 | 0.82 | LTA4H (0.47) | C5AR1PPIAMEN1MAPTKMT2A | |
| SCHEMBL6686056 | 0.82 | C5AR1 (0.54) | C5AR1MEN1MAPTKMT2ACTSV | |
| Hydrochloric Acid SCHEMBL6680952 | 0.81 | PPIA (0.43) | C5AR1PPIAMEN1MAPTKMT2A | |
| SCHEMBL6681426 | 0.78 | CYP2C9 (0.42) | PPIAMEN1MAPTKMT2ACTSV | |
| SCHEMBL27515135 | 0.78 | C5AR1 (0.53) | C5AR1MAPT | |
| SCHEMBL28747646 | 0.78 | C5AR1 (0.46) | C5AR1MAPTF2F10PRSS1 | |
| SCHEMBL27515134 | 0.78 | C5AR1 (0.47) | C5AR1PPIAMEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |