Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025152 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL5427708 | 0.84 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27452198 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27725396 | 0.82 | PTPN22 (0.39) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27704794 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27304277 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27780588 | 0.75 | ALDH1A1 (0.49) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL28037612 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL8895371 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27661280 | 0.71 | ALDH1A1 (0.61) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154701-A | 8-fluoro-anthracyclines, process for their preparation and pharmaceutical compositions containing them | MENARINI FARMA IND (IT) | 1997-07-16 | — | — | CN | disclosed |