Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515368 | 0.82 | ALDH1A1 (0.35) | ERN1ABCG2GPR35MEN1ALDH1A1 | |
| SCHEMBL5427708 | 0.81 | ALDH1A1 (0.44) | ABCG2MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL27780588 | 0.79 | ALDH1A1 (0.49) | ABCG2MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL27304277 | 0.77 | ALDH1A1 (0.53) | ABCG2GPR35MEN1ALDH1A1KMT2A | |
| SCHEMBL27348528 | 0.75 | PTPN22 (0.46) | PTPN22ERN1ABCG2GPR35MEN1 | |
| SCHEMBL27847437 | 0.75 | CYP1A2 (0.43) | ERN1ABCG2GPR35MEN1ALDH1A1 | |
| SCHEMBL27452198 | 0.75 | ALDH1A1 (0.47) | ERN1ABCG2GPR35MEN1ALDH1A1 | |
| SCHEMBL28302678 | 0.74 | MEN1 (0.43) | ERN1MEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL28037612 | 0.73 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2AKDM4ETP53 | |
| SCHEMBL2113598 | 0.73 | CYP1A2 (0.62) | PTPN22CDK2ABCG2PTPN11RNASEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189318-B | Reversibly thermochromic compositions | CIBA SC HOLDING AG | 2012-06-20 | — | — | CN | claimed |
| CN-101189318-A | Reversibly thermochromic compositions | CIBA SC HOLDING AG (CH) | 2008-05-28 | — | — | CN | claimed |
| CN-101189318-B | Reversibly thermochromic compositions | CIBA SC HOLDING AG | 2012-06-20 | — | — | CN | disclosed |
| CN-101189318-A | Reversibly thermochromic compositions | CIBA SC HOLDING AG (CH) | 2008-05-28 | — | — | CN | disclosed |