Dinitrophenylene

Dinitrophenylene

SCHEMBL27516554

CC(C)(C)c1ccc(O)cc1.O=[N+]([O-])c1cccc([N+](=O)[O-])c1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
LMNA P02545 3/20 0.59
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
MAPT P10636 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
NPC1 O15118 1/20 0.59
NFKB1 P19838 1/20 0.59
RAB9A P51151 1/20 0.59
NFKB2 Q00653 1/20 0.59
RELA Q04206 1/20 0.59
TSHR P16473 3/20 0.58
ALOX15 P16050 1/20 0.58
TYR P14679 1/20 0.53
PTPRC P08575 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
GAA P10253 2/20 0.49
ACHE P22303 1/20 0.49
HTT P42858 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27496976 0.86 LMNA (0.61) ALDH1A1LMNAMEN1KMT2AMAPT
P-Nitrophenol SCHEMBL28178085 0.86 LMNA (0.61) ALDH1A1LMNAMEN1KMT2AMAPT
Dinitrophenylene SCHEMBL27738809 0.86 TSHR (0.77) ALDH1A1LMNAMEN1KMT2AMAPT
Tetrabuthylammonium SCHEMBL27500535 0.85 ALDH1A1 (0.47) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL8772960 0.81 ALDH1A1 (0.57) ALDH1A1LMNAMEN1KMT2AMAPT
Dinitrophenylene SCHEMBL27278805 0.81 ALDH1A1 (0.63) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL179286 0.80 PTPRC (0.63) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL31496742 0.80 PTPRC (0.63) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL1622291 0.80 MAPT (0.56) ALDH1A1LMNAMEN1KMT2AMAPT
SCHEMBL30469256 0.80 MAPT (0.56) ALDH1A1LMNAMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103214378-A Synthesis method of high-purity butralin UNIV HEILONGJIANG 2013-07-24 CN disclosed
CN-101337860-B Method and device for recovering low-boiling-point compound from heavy tar of phenylethene ZHIGANG XU 2012-07-25 CN disclosed
CN-101056832-B Method of inhibiting polymerization for copolymer containing divinylbenzene and aromatic vinyl compound HAKUTO CO.,LTD. (JP) 2011-12-07 CN disclosed
CN-101823967-A Synthesis process of 2, 6-dinitro-4-alkylphenol NANTONG ZHENGYAN PIGMENT CHEMICAL CO LTD 2010-09-08 CN disclosed
CN-101337860-A Method and device for recovering low-boiling-point compound from heavy tar of phenylethene ZHIGANG XU (CN) 2009-01-07 CN disclosed
CN-101056832-A Method of inhibiting polymerization for copolymer containing divinylbenzene and aromatic vinyl compound HAKUTO KK (JP) 2007-10-17 CN disclosed
CN-1247522-C Green nitration method of phenol type compound SHANGHAI INST ORGANIC CHEM (CN) 2006-03-29 CN disclosed
CN-1230382-C Green nitrifying method by using Hf compound to catalyze compounds of phenols and aromatic ether SHANGHAI INST ORGANIC CHEM (CN) 2005-12-07 CN disclosed
CN-1539746-A Green nitrifying method by using Hf compound to catalyze compounds of phenols and aromatic ether 中国科学院上海有机化学研究所 2004-10-27 CN disclosed
CN-1410415-A Green nitration method of phenol type compound SHANGHAI INST ORGANIC CHEM (CN) 2003-04-16 CN disclosed
CN-1200371-A Prepn. process for 4-substituted dinitroanilines FRANCAIS PROD IND CFPI (FR) 1998-12-02 CN disclosed