Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330486 | 0.98 | APOBEC3A (0.64) | APOBEC3AAPOBEC3GKEAP1TSHRSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL2386168 | 0.91 | APOBEC3A (0.67) | APOBEC3AAPOBEC3GKEAP1TSHRSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL5345728 | 0.86 | APOBEC3A (0.61) | APOBEC3AAPOBEC3GTSHRSMN1; SMN2ACHE | |
| SCHEMBL331180 | 0.84 | APOBEC3A (0.58) | APOBEC3AAPOBEC3GTSHRSMN1; SMN2ACHE | |
| SCHEMBL331232 | 0.84 | APOBEC3A (0.44) | APOBEC3AAPOBEC3GKEAP1TSHRSMN1; SMN2 | |
| SCHEMBL330485 | 0.84 | APOBEC3A (0.64) | APOBEC3AAPOBEC3GKEAP1ACHEBCHE | |
| Sulfuric Acid SCHEMBL27613503 | 0.83 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GTSHRSMN1; SMN2ACHE | |
| SCHEMBL330823 | 0.83 | TSHR (0.67) | APOBEC3AAPOBEC3GTSHRSMN1; SMN2ACHE | |
| SCHEMBL27602968 | 0.83 | APOBEC3A (0.56) | APOBEC3AAPOBEC3GTSHRSMN1; SMN2ACHE | |
| Ammonia Solution, Strong SCHEMBL27920809 | 0.83 | APOBEC3A (0.88) | APOBEC3AAPOBEC3GTSHRACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308426-C | Low residue aqueous compositions for hard surface cleaning and disinfecting | RECKITT & COLMAN INC (US) | 2007-04-04 | — | — | CN | disclosed |
| CN-1234065-A | Low residue aqueous hard surface cleaning and desinfecting compositions | RECKITT & COLMAN INC (US) | 1999-11-03 | — | — | CN | disclosed |