Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909338 | 0.81 | MAOA (0.47) | MAOAPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL1337795 | 0.79 | MAOA (0.46) | MAOAPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL7837160 | 0.77 | PDE3A (0.47) | MAOAPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL2907694 | 0.76 | MAOA (0.43) | MAOAPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL1337297 | 0.76 | PDE3B (0.46) | MAOAPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL2905838 | 0.76 | MAOA (0.43) | MAOAPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL28231525 | 0.74 | ALOX15 (0.54) | MAOAPDE3BPDE3AKDM4E | |
| SCHEMBL2639183 | 0.74 | PDGFRB (0.52) | PDE3BPDE3APDGFRBPDGFRAKDM4E | |
| SCHEMBL27545732 | 0.74 | MAOA (0.44) | MAOAKDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL13870932 | 0.73 | MAOA (0.44) | MAOAPDE3BPDE3APDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1281585-C | Cyclic diamine compounds having fused-ring groups | KOWA CO (JP) | 2006-10-25 | — | — | CN | disclosed |
| CN-1599717-A | Cyclic diamine compounds having fused-ring groups | KOWA CO (JP) | 2005-03-23 | — | — | CN | disclosed |