Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.96 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | HNF4A | P41235 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132986 | 0.98 | BCAT2 (1.00) | BCAT2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29427545 | 0.98 | BCAT2 (1.00) | BCAT2NPC1RAB9AMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28275782 | 0.96 | BCAT2 (0.96) | BCAT2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28355265 | 0.96 | BCAT2 (0.96) | BCAT2NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5180095 | 0.96 | BCAT2 (0.96) | BCAT2NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1785690 | 0.96 | BCAT2 (0.96) | BCAT2NPC1RAB9AMEN1KMT2A | |
| Urea SCHEMBL28572437 | 0.96 | BCAT2 (0.96) | BCAT2NPC1RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27487444 | 0.96 | BCAT2 (0.96) | BCAT2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31140008 | 0.94 | BCAT2 (0.92) | BCAT2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16149659 | 0.93 | BCAT2 (0.91) | BCAT2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247569-C | Novel pyrimidyl sulfamide compounds with anti-tumor activity and their salts | XINXING MEDICINE CO LTD SHANGH (CN) | 2006-03-29 | — | — | CN | disclosed |
| CN-1629155-A | Pyrimidinyl carboxylic acid amide compounds with anti-tumor activity and salts thereof | SHANGHAI XINXING MEDICAL CO LT (CN) | 2005-06-22 | — | — | CN | disclosed |
| CN-1587263-A | Novel pyrimidyl sulfamide compounds with anti-tumor activity and their salts | XINXING MEDICINE CO LTD SHANGH (CN) | 2005-03-02 | — | — | CN | disclosed |