SCHEMBL28355265

SCHEMBL28355265

NC(=O)c1ccccc1-c1ccccc1.[NaH]

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 2/20 0.96
NPC1 O15118 1/20 0.56
RAB9A P51151 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CHRNB2 P17787 2/20 0.53
CHRNB4 P30926 2/20 0.53
CHRNA3 P32297 2/20 0.53
CHRNA4 P43681 2/20 0.53
HNF4A P41235 1/20 0.52
TSHR P16473 2/20 0.50
PARP1 P09874 1/20 0.50
RECQL P46063 1/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
IKBKB O14920 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132986 0.98 BCAT2 (1.00) BCAT2NPC1RAB9AMEN1KMT2A
SCHEMBL29427545 0.98 BCAT2 (1.00) BCAT2NPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL27487444 0.96 BCAT2 (0.96) BCAT2NPC1RAB9AMEN1KMT2A
Ammonia Solution, Strong SCHEMBL28275782 0.96 BCAT2 (0.96) BCAT2NPC1RAB9AMEN1KMT2A
Urea SCHEMBL28572437 0.96 BCAT2 (0.96) BCAT2NPC1RAB9AMEN1KMT2A
Methane SCHEMBL27520060 0.96 BCAT2 (0.96) BCAT2NPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL1785690 0.96 BCAT2 (0.96) BCAT2NPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL5180095 0.96 BCAT2 (0.96) BCAT2NPC1RAB9AMEN1KMT2A
SCHEMBL31140008 0.94 BCAT2 (0.92) BCAT2NPC1RAB9AMEN1KMT2A
SCHEMBL16149659 0.93 BCAT2 (0.91) BCAT2NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110621157-A Use of difluoro- (2-hydroxypropyl) pyridine compounds as fungicides for controlling phytopathogenic fungi of rice 美国陶氏益农公司 2019-12-27 CN disclosed