SCHEMBL27520104

SCHEMBL27520104

C=C(O[Si](C)(C)C)C(=O)OCCC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.40
HCAR2 Q8TDS4 1/20 0.38
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.34
ALDH1A1 P00352 4/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
ATM Q13315 1/20 0.32
APP P05067 1/20 0.32
ESR1 P03372 1/20 0.32
CHRM1 P11229 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDR P35968 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALOX5 P09917 1/20 0.31
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3534657 0.83 ALDH1A1 (0.45) TSHRTHRBALDH1A1GAASMN1; SMN2
SCHEMBL6234359 0.81 TSHR (0.47) TSHRHCAR2THRBHPGDALDH1A1
SCHEMBL9546011 0.79 TSHR (0.37) TSHRTHRBHPGDALDH1A1
SCHEMBL9546073 0.78
SCHEMBL6283556 0.77 THRB (0.45) TSHRHCAR2THRBALDH1A1GAA
SCHEMBL3012938 0.77 TSHR (0.44) TSHRHCAR2THRBHPGDALDH1A1
SCHEMBL2173680 0.77 TSHR (0.35) TSHRHPGDTDP1
SCHEMBL19582845 0.75 TSHR (0.42) TSHRHCAR2THRBHPGDALDH1A1
SCHEMBL6679127 0.75 TSHR (0.42) TSHRHCAR2THRBHPGDALDH1A1
SCHEMBL15452860 0.75 TSHR (0.42) TSHRHCAR2THRBHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN claimed
CN-101189271-A Functional materials and novel methods for the fabrication of microfluidic devices UNIV NORTH CAROLINA (US) 2008-05-28 CN claimed
CN-109790243-A Three block prepolymer and its purposes in silicone hydrogels 庄臣及庄臣视力保护公司 2019-05-21 CN disclosed
CN-108530664-A The manufacturing method of adhesion inhibiting properties hard coating film 理研科技株式会社 2018-09-14 CN disclosed
CN-105358262-B Method for producing anti-blocking hard coat film 理研科技株式会社 2018-05-01 CN disclosed
CN-105358262-A Method for producing anti-blocking hard coat film RIKEN TECHNOS CORP 2016-02-24 CN disclosed
CN-105219149-A Light screening material and the display unit comprising light screening material LG DISPLAY CO LTD 2016-01-06 CN disclosed
CN-104812564-A Article having glass-like design RIKEN TECHNOS CORP 2015-07-29 CN disclosed
CN-101578043-B Antimicrobial polymeric articles, processes to prepare them and methods of their use JOHNSON & JOHNSON VISION CARE 2015-07-22 CN disclosed
CN-103717701-A Coated phosphors and light emitting devices including the same KE RUI 2014-04-09 CN disclosed
CN-101604607-A Coating composition for interconnection part of electrode and comprise its plasma display SAMSUNG SDI CO LTD (KR) 2009-12-16 CN disclosed
CN-1289277-C Method for coating articles by mold transfer JOHNSON & JOHNSON VISION CARE (US) 2006-12-13 CN disclosed
CN-1281282-C Antibacterial contact lens and preparation method thereof JOHNSON & JOHNSON VISON CARE I (US) 2006-10-25 CN disclosed
CN-1264230-C Packaging material for electronic component case SHOWA DENKO KK (JP) 2006-07-12 CN disclosed
CN-1742061-A Water-based ink, recorded image using the same, and method for forming image CANON KK (JP) 2006-03-01 CN disclosed
CN-1671779-A Ambient cured coatings and coated rubber products therefrom LORD CORP (US) 2005-09-21 CN disclosed
CN-1564732-A Method for coating articles by mold transfer JOHNSON & JOHNSON VISION CARE (US) 2005-01-12 CN disclosed
CN-1541119-A Antibacterial contact lens and preparation method thereof 2004-10-27 CN disclosed
CN-1475037-A Packaging material for electronic-part case, and others �Ѻ͵繤��װ��ʽ���� 2004-02-11 CN disclosed
CN-1378576-A Pigment dispersions containing ABC-block polymer dispersant DU PONT (US) 2002-11-06 CN disclosed