Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11195785 | 0.85 | HTT (0.54) | HSP90AB1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL10990106 | 0.85 | HSP90AB1 (0.61) | HSP90AB1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL1144066 | 0.82 | ALDH1A1 (0.69) | HSP90AB1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16432142 | 0.82 | ALDH1A1 (0.69) | HSP90AB1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL29712843 | 0.82 | ALDH1A1 (0.69) | HSP90AB1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6579360 | 0.81 | PTPN1 (0.48) | HSP90AB1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL481085 | 0.80 | HSP90AB1 (1.00) | HSP90AB1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4706474 | 0.80 | HSP90AB1 (1.00) | HSP90AB1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29457585 | 0.80 | HSP90AB1 (1.00) | HSP90AB1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10031578 | 0.79 | CHRM2 (0.52) | HSP90AB1MAPTALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228448-C | Process for preparing chiral medicine intermediate (R)-2-halogen-1-(substituted phenyl) ethanol | TIANJIN NANKAI GUARD CO LTD (CN) | 2005-11-23 | — | — | CN | disclosed |
| CN-1554767-A | Process for preparing chiral medicine intermediate (R)-2-halogen-1-(substituted phenyl) ethanol | 天津南开戈德集团有限公司 | 2004-12-15 | — | — | CN | disclosed |