Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 4/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21055979 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPK1HIF1AHSD17B10GSK3B | |
| SCHEMBL27520109 | 0.82 | HSP90AB1 (0.67) | ALDH1A1MAPK1HIF1AHSD17B10ESRRB | |
| SCHEMBL6579360 | 0.82 | PTPN1 (0.48) | ALDH1A1MAPK1HIF1AHSD17B10GSK3B | |
| SCHEMBL4828627 | 0.82 | HSP90AB1 (0.66) | ALDH1A1MAPK1HIF1AMAPTRAB9A | |
| SCHEMBL30269774 | 0.82 | HSP90AB1 (0.66) | ALDH1A1MAPK1HIF1AMAPTRAB9A | |
| SCHEMBL29481555 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPK1HIF1AGSK3BMAPT | |
| SCHEMBL1691536 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPK1HIF1AGSK3BMAPT | |
| SCHEMBL11195785 | 0.79 | HTT (0.54) | ALDH1A1MAPK1HIF1AHSD17B10ESRRB | |
| SCHEMBL9733934 | 0.79 | KMT2A (0.45) | ALDH1A1MAPK1HIF1AHSD17B10MAPT | |
| SCHEMBL1758840 | 0.79 | HSD17B10 (0.54) | ALDH1A1HSD17B10ESRRBESRRGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027592-B1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-26 | — | — | EP | disclosed |
| US-9695123-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-04 | — | — | US | disclosed |
| US-9695123-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-04 | — | — | US | disclosed |
| US-9695123-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-04 | — | — | US | disclosed |
| US-20160168095-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | US | disclosed |
| US-20160168095-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | US | disclosed |
| US-20160168095-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-16 | — | — | US | disclosed |
| EP-3027592-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015014733-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-05 | — | — | WO | disclosed |
| WO-2015014733-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168095-A1 | NOVEL MICROBIOCIDES | MSR1, C1R, C5AR1 | ALDH1A1 3060/4885MAPK1 1823/4885HIF1A 1649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.