Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460078 | 0.93 | L3MBTL1 (0.39) | L3MBTL1TDP1MAPTHPGDMAPK1 | |
| SCHEMBL316261 | 0.86 | CYP1A2 (0.41) | L3MBTL1TDP1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL2806331 | 0.86 | SMN1; SMN2 (0.40) | L3MBTL1TDP1MAPTHPGDMAPK1 | |
| SCHEMBL3118111 | 0.86 | L3MBTL1 (0.37) | L3MBTL1TDP1MAPTHPGDMAPK1 | |
| SCHEMBL314353 | 0.84 | KDM4E (0.37) | L3MBTL1TDP1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL182703 | 0.84 | L3MBTL1 (0.38) | L3MBTL1TDP1MAPTHPGDMAPK1 | |
| SCHEMBL7389250 | 0.82 | KDM4E (0.42) | L3MBTL1TDP1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL7390535 | 0.82 | TUBB1 (0.44) | L3MBTL1TDP1MAPTSMN1; SMN2PRSS1 | |
| SCHEMBL188489 | 0.81 | HTR7 (0.44) | SMN1; SMN2ALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL159256 | 0.79 | KDM4E (0.42) | MAPTMAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048037-A | N- (aryloxyalkyl) heteroarylpiperidines and heteroarylpiperazines, their preparation and their use as pharmaceuticals | HOECHST ROUSSEL PHARMA (US) | 1990-12-26 | — | — | CN | disclosed |