Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 4/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27517441 | 0.82 | NPC1 (0.54) | DHODHAKR1C2AKR1C1NPC1RAB9A | |
| SCHEMBL27498799 | 0.78 | DHODH (0.56) | DHODHMEN1LMNAKMT2ATTR | |
| SCHEMBL16608990 | 0.77 | RPA1 (0.58) | RPA1DHODHKMOSMN1; SMN2CASP1 | |
| SCHEMBL27709822 | 0.75 | ALDH1A1 (0.47) | DHODHAKR1C2KMOSMN1; SMN2CASP1 | |
| SCHEMBL11695681 | 0.75 | AKR1C2 (0.58) | RPA1AKR1C2AKR1C1KMO | |
| SCHEMBL27631357 | 0.74 | DHODH (0.58) | DHODHKMOTTR | |
| SCHEMBL3979148 | 0.74 | ACMSD (0.59) | RPA1KMOMEN1LMNAKMT2A | |
| SCHEMBL19730792 | 0.74 | RARB (0.48) | DHODH | |
| SCHEMBL24524864 | 0.74 | SLC1A3 (0.40) | RPA1AKR1C2KMOCASP1PTGS2 | |
| SCHEMBL31161066 | 0.73 | CHRM1 (0.53) | RPA1DHODHAKR1C2AKR1C1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |