SCHEMBL27520177

SCHEMBL27520177

CCC(=O)C1CNCCN1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.33
CHRNA3 P32297 3/20 0.33
CHRNA4 P43681 3/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA7 P36544 2/20 0.33
CHRNB3 Q05901 1/20 0.32
CHRNA6 Q15825 1/20 0.32
SLC6A1 P30531 2/20 0.31
GABRA5 P31644 2/20 0.31
GABRB2 P47870 2/20 0.31
SLC6A12 P48065 2/20 0.31
SLC6A11 P48066 2/20 0.31
SLC6A13 Q9NSD5 2/20 0.31
GABRA1 P14867 1/20 0.31
GABRR1 P24046 1/20 0.31
GABRA4 P48169 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10587925 0.86 CHRNB2 (0.40) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL8499848 0.85 CHRNB2 (0.32) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL15263875 0.83 SLC6A1 (0.34) SLC6A1GABRA5GABRB2SLC6A12SLC6A11
SCHEMBL17087644 0.80 SMN1; SMN2 (0.42) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL3272707 0.80 SLC6A1 (0.36) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL4383814 0.80 SLC6A1 (0.36) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL15542301 0.80 SLC6A1 (0.36) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL8369334 0.77 F2 (0.31)
SCHEMBL23827563 0.77 KDM4E (0.37) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6
SCHEMBL17276241 0.77 SLC6A1 (0.31) CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1231468-C Chemical compounds GLAXO GROUP LTD (GB) 2005-12-14 CN disclosed
CN-1483025-A Chemical compounds 2004-03-17 CN disclosed