Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2883476 | 0.83 | HRH1 (0.50) | SMN1; SMN2ESR1POLBSTAT3ESR2 | |
| SCHEMBL2886310 | 0.80 | HRH1 (0.54) | SMN1; SMN2ESR1POLBSTAT3ESR2 | |
| SCHEMBL17997542 | 0.79 | CHRM2 (0.51) | SMN1; SMN2ESR1POLBSTAT3ESR2 | |
| SCHEMBL11337822 | 0.78 | ADRA1D (0.47) | POLBL3MBTL1HRH1CYP2D6CYP1A2 | |
| SCHEMBL14366318 | 0.78 | TSHR (0.46) | SMN1; SMN2ESR1POLBSTAT3ESR2 | |
| SCHEMBL21241290 | 0.77 | ADRA1D (0.39) | SMN1; SMN2ESR1POLBSTAT3ESR2 | |
| SCHEMBL13610468 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2ESR1POLBSTAT3ESR2 | |
| SCHEMBL41191 | 0.76 | L3MBTL1 (0.59) | SMN1; SMN2L3MBTL1HRH1HRH3LMNA | |
| SCHEMBL29830938 | 0.76 | L3MBTL1 (0.59) | SMN1; SMN2L3MBTL1HRH1HRH3LMNA | |
| SCHEMBL10565206 | 0.75 | NPC1 (0.41) | SMN1; SMN2L3MBTL1CYP2D6CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674190-B | A kind of synthetic method of 2-thenylaminine | 台州市创源工业技术有限公司 | 2019-05-10 | — | — | CN | claimed |
| CN-106800519-B | Ultrasonic radiation method rapid synthesis bridging type pair, the universal method and application of three, four amide derivatives | 中南民族大学 | 2019-03-12 | — | — | CN | claimed |
| CN-109232593-A | A kind of fluorescence probe and preparation method thereof detecting ferric ion | 华南理工大学 | 2019-01-18 | — | — | CN | claimed |
| CN-108997546-A | A kind of carbon containing nitrogen and the benzoxazine resin of azo structure and preparation method thereof | 西南石油大学 | 2018-12-14 | — | — | CN | claimed |
| CN-108997548-A | A kind of photolytic activity benzoxazine resin and preparation method thereof | 西南石油大学 | 2018-12-14 | — | — | CN | claimed |
| CN-106084286-B | A kind of halogen-free expansion type flame-proof carbon forming agent compound and preparation method thereof | 浙江旭森非卤消烟阻燃剂有限公司 | 2018-10-30 | — | — | CN | claimed |
| CN-108461632-A | Perovskite composite structure | 华邦电子股份有限公司 | 2018-08-28 | — | — | CN | claimed |
| CN-107523015-A | CNT montmorillonite self-assembled nanometer powder is grafted the preparation method of galss fiber reinforced resin composite | 河海大学 | 2017-12-29 | — | — | CN | claimed |
| CN-107445142-A | A kind of preparation method of CNT montmorillonite self-assembled nanometer powder | 河海大学 | 2017-12-08 | — | — | CN | claimed |
| CN-107338236-A | The functional material for being used to fix Azodrin degradation bacteria being modified based on acrylic resin | 光合强化（北京）生物科技有限公司 | 2017-11-10 | — | — | CN | claimed |
| CN-104620104-B | Affinity Reagents for Protein Purification | 非凡食品有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-106349147-A | Synthetic method of pyrrole derivatives | 南阳师范学院 | 2017-01-25 | — | — | CN | claimed |
| CN-105968351-A | Sulfur-containing macromolecule triazine polymer and preparation method thereof | 浙江旭森非卤消烟阻燃剂有限公司 | 2016-09-28 | — | — | CN | claimed |
| CN-105885045-A | Organic selenium triazine polymer and preparation method thereof | 浙江旭森非卤消烟阻燃剂有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-105585583-A | Non-peptide IAP (inhibitor of apoptosis protein) antagonist as well as synthetic method and application thereof | UNIV GUANGDONG TECHNOLOGY | 2016-05-18 | — | — | CN | claimed |
| CN-105566447-A | Peptoid antagonist of anti-apoptosis protein and synthesis method and application of peptoid antagonist | UNIV GUANGDONG TECHNOLOGY | 2016-05-11 | — | — | CN | claimed |
| CN-105237466-A | Method for compounding tri-substituted pyridine derivatives | UNIV NANYANG NORMAL | 2016-01-13 | — | — | CN | claimed |
| CN-102875564-B | The nitrogen of tool anti-tumor activity replaces podophyllum derivative and its production and use | Hubei Industry University (CN) | 2015-10-21 | — | — | CN | claimed |
| CN-102875564-A | Nitrogen substitution podophyllum type derivatives with antitumor activity and preparation method and application thereof | UNIV HUBEI TECHNOLOGY | 2013-01-16 | — | — | CN | claimed |
| EP-0745080-B1 | NOVEL MERCAPTOACETYLAMIDE DISULFIDE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE | MERRELL PHARMA INC (US) | 1999-03-03 | — | — | EP | claimed |