Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27521261 | 0.87 | KDM4E (0.33) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL27502864 | 0.82 | CYP2A6 (0.40) | KDM4ESMN1; SMN2 | |
| SCHEMBL27529595 | 0.80 | SMN1; SMN2 (0.36) | KDM4ELMNAPOLBSMN1; SMN2KMT2A | |
| SCHEMBL27504605 | 0.77 | GRIA1 (0.41) | KMT2A | |
| SCHEMBL27504281 | 0.77 | ALDH1A1 (0.36) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL27520393 | 0.74 | KDM4E (0.34) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL27520392 | 0.73 | CHRM2 (0.37) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL27562064 | 0.72 | KDM4E (0.33) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL27537622 | 0.71 | CHRM2 (0.33) | KDM4ELMNACYP1A2POLBCCR1 | |
| SCHEMBL27503537 | 0.71 | GRM5 (0.35) | KDM4ELMNACYP1A2POLBCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1245386-C | 1, 2-dihydropyridine compound, preparation method and application thereof | EISAI CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| CN-1436172-A | 1, 2-dihydropyridine compound, preparation method and application thereof | EISAI CO LTD (JP) | 2003-08-13 | — | — | CN | disclosed |