Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CCR1 | P32246 | 3/20 | 0.34 |
| ▸ | CCR5 | P51681 | 3/20 | 0.34 |
| ▸ | CCR8 | P51685 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27502491 | 0.86 | KDM4E (0.34) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29290942 | 0.81 | SMN1; SMN2 (0.41) | KDM4EPOLBSMN1; SMN2EP300KAT2B | |
| SCHEMBL27522973 | 0.81 | POLB (0.35) | KDM4EPOLBSMN1; SMN2EP300KAT2B | |
| SCHEMBL29290945 | 0.81 | POLB (0.35) | KDM4EPOLBSMN1; SMN2EP300KAT2B | |
| SCHEMBL29290951 | 0.77 | POLB (0.35) | KDM4EPOLBSMN1; SMN2EP300KAT2B | |
| SCHEMBL27520403 | 0.74 | KDM4E (0.33) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL27504274 | 0.73 | POLB (0.37) | KDM4EPOLBCYP1A2SMN1; SMN2EP300 | |
| SCHEMBL29290947 | 0.67 | SMN1; SMN2 (0.41) | KDM4EPOLBCYP1A2SMN1; SMN2EP300 | |
| SCHEMBL27521874 | 0.66 | KDM4E (0.38) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL31630557 | 0.59 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1245386-C | 1, 2-dihydropyridine compound, preparation method and application thereof | EISAI CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| CN-1436172-A | 1, 2-dihydropyridine compound, preparation method and application thereof | EISAI CO LTD (JP) | 2003-08-13 | — | — | CN | disclosed |