Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27521258 | 0.81 | ACHE (0.37) | ACHETAAR1ESR2NISCHPGR | |
| Hydrochloric Acid SCHEMBL27521217 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL27566934 | 0.80 | ACHE (0.36) | ACHETAAR1ESR2NISCHPGR | |
| Hydrochloric Acid SCHEMBL27522508 | 0.79 | NISCH (0.38) | NISCHNOTUMIDO1 | |
| Hydrochloric Acid SCHEMBL27546010 | 0.79 | ACHE (0.35) | ACHETAAR1ESR2NISCHPGR | |
| Hydrochloric Acid SCHEMBL27566935 | 0.77 | ACHE (0.36) | ACHETAAR1ESR2PGRTNKS2 | |
| Hydrochloric Acid SCHEMBL27546012 | 0.77 | ACHE (0.36) | ACHETAAR1ESR2PGRTNKS2 | |
| Hydrochloric Acid SCHEMBL27546303 | 0.76 | CYP2A6 (0.35) | ESR2NISCHCYP17A1CYP3A4CYP11B1 | |
| Hydrochloric Acid SCHEMBL7926764 | 0.74 | ACHE (0.32) | ACHETAAR1ESR2NISCHADORA2A | |
| Hydrochloric Acid SCHEMBL7938809 | 0.74 | ACHE (0.33) | ACHETAAR1ESR2PGRTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274360-A | Processes for prepn. of metallocene complexes | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |