Urea

Urea

SCHEMBL27520574

NC(=O)NC(=O)O.NC(N)=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.47
LMNA P02545 3/20 0.43
ALDH1A1 P00352 1/20 0.43
OR51E2 Q9H255 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TSHR P16473 2/20 0.41
NFKB1 P19838 2/20 0.41
CYP1A2 P05177 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
THPO P40225 1/20 0.41
CA2 P00918 1/20 0.41
CYP3A4 P08684 1/20 0.41
CA5A P35218 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
CA9 Q16790 1/20 0.41
ACHE P22303 1/20 0.40
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL28012617 0.97 ACHE (0.47) CRBNLMNAALDH1A1OR51E2TDP1
SCHEMBL9425846 0.96 CRBN (0.50) CRBNLMNAALDH1A1OR51E2TDP1
SCHEMBL22493 0.96
Hydrogen Peroxide SCHEMBL28780383 0.96
SCHEMBL23002882 0.93
SCHEMBL4576144 0.93 CRBN (0.47) CRBNLMNAALDH1A1OR51E2TDP1
SCHEMBL17353590 0.93
Hydrochloric Acid SCHEMBL2672461 0.93
Water SCHEMBL6337702 0.93
Hydrogen Sulfide SCHEMBL28206899 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406566-A Polyisocyantates composition, polyurethane resin and coating 三井化学株式会社 2017-11-28 CN disclosed
CN-1274736-C Process for catalytic dimerization of isocyanates RHODIA CHIMIE SA (FR) 2006-09-13 CN disclosed
CN-1474841-A Method for catalytic dimerization of isocyanates �޵��ǻ�ѧ��˾ 2004-02-11 CN disclosed