SCHEMBL4576144

SCHEMBL4576144

NC(=O)NC(=O)O.NC(=O)NC(N)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.47
LMNA P02545 3/20 0.41
TSHR P16473 2/20 0.41
NFKB1 P19838 2/20 0.41
CYP1A2 P05177 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
THPO P40225 1/20 0.41
CA2 P00918 1/20 0.41
CYP3A4 P08684 1/20 0.41
CA5A P35218 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
CA9 Q16790 1/20 0.41
ACHE P22303 1/20 0.40
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
ALDH1A1 P00352 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL28780383 0.96
SCHEMBL9425846 0.96 CRBN (0.50) CRBNLMNATSHRNFKB1CYP1A2
SCHEMBL22493 0.96
SCHEMBL23002882 0.93
SCHEMBL17353590 0.93
Urea SCHEMBL27520574 0.93 CRBN (0.47) CRBNLMNATSHRNFKB1CYP1A2
Hydrochloric Acid SCHEMBL2672461 0.93
Ammonia Solution, Strong SCHEMBL27866084 0.93
Water SCHEMBL6337702 0.93
SCHEMBL28220720 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262261-A1 STABLE LIQUID BIURET MODIFIED AND BIURET ALLOPHANATE MODIFIED TOLUENE DIISOCYANATES, PREPOLYMERS THEREOF, AND PROCESSES FOR THEIR PREPARATION BAYER MATERIALSCIENCE LLC (US) 2008-10-23 US claimed
US-7378543-B2 Stable liquid biuret modified and biuret allophanate modified toluene diisocyanates, prepolymers thereof, and processes for their preparation BAYER MATERIALSCIENCE LLC (US) 2008-05-27 US claimed
US-20080033203-A1 Stable liquid biuret modified and biuret allophanate modified toluene diisocyanates, prepolymers thereof, and processes for their preparation SLACK WILLIAM E 2008-02-07 US claimed
EP-1651594-A2 STABLE LIQUID BIURET MODIFIED AND BIURET ALLOPHANATE MODIFIED TOLUENE DIISOCYANATES, PREPOLYMERS THEREOF, AND PROCESSES FOR THEIR PREPARATION Bayer MaterialScience LLC (US) 2006-05-03 EP claimed
WO-2005009945-A2 STABLE LIQUID BIURET MODIFIED AND BIURET ALLOPHANATE MODIFIED TOLUENE DIISOCYANATES, PREPOLYMERS THEREOF, AND PROCESSES FOR THEIR PREPARATION BAYER MATERIALSCIENCE LLC (US) 2005-02-03 WO claimed
US-20050020795-A1 STABLE LIQUID BIURET MODIFIED AND BIURET ALLOPHANATE MODIFIED DIPHENYLMETHANE DIISOCYANATES, PREPOLYMERS THEREOF, AND PROCESSES FOR THEIR PREPARATION COVESTRO LLC 2005-01-27 US claimed
US-20050020765-A1 Stable liquid biuret modified and biuret allophanate modified toluene diisocyanates, prepolymers thereof, and processes for their preparation BAYER MATERIALSCIENCE LLC 2005-01-27 US claimed
US-6838542-B1 Stable liquid biuret modified and biuret allophanate modified diphenylmethane diisocyanates, prepolymers thereof, and processes for their preparation BAYER MATERIALSCIENCE LLC (US) 2005-01-04 US claimed
JP-4309516-A None JP disclosed
CN-113755112-B Adhesive sheet, adherend with adhesive sheet, and method for using adhesive sheet 爱天思株式会社 2024-10-18 CN disclosed
CN-118421251-A Adhesive and adhesive sheet 爱天思株式会社 2024-08-02 CN disclosed
CN-114206459-B Adhesive and adhesive sheet 爱天思株式会社 2024-07-12 CN disclosed
CN-118290706-A Preparation method of polyisocyanate composition 万华化学(宁波)有限公司 2024-07-05 CN disclosed
EP-3356441-B1 BIURET POLYISOCYANATE COMPOSITION VENCOREX FRANCE (FR) 2024-05-22 EP disclosed
EP-0929325-A1 ePTFE SMALL CALIBER VASCULAR GRAFTS WITH SIGNIFICANT PATENCY ENHANCEMENT VIA A SURFACE COATING WHICH CONTAINS COVALENTLY BONDED HEPARIN Meadox Medicals, Inc. (US) 1999-07-21 EP disclosed
WO-1998010806-A1 ePTFE SMALL CALIBER VASCULAR GRAFTS WITH SIGNIFICANT PATENCY ENHANCEMENT VIA A SURFACE COATING WHICH CONTAINS COVALENTLY BONDED HEPARIN MEADOX MEDICALS, INC. (US) 1998-03-19 WO disclosed
CN-1130196-A Method for preparing low fogging polyurethane foam and special poly suboxygen alkyl-polyol for the same BASF AG (DE) 1996-09-04 CN disclosed
US-5473032-A Includes acrylic copolymer having hydroxyl groups HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1995-12-05 US disclosed
JP-H04309516-A PRODUCTION OF THERMOPLASTIC POLYURETHANE RESIN SANYO CHEM IND LTD 1992-11-02 JP disclosed
US-4611083-A FLEXIBLE POLYURETHANE FOAMS BASF AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080033203-A1 Stable liquid biuret modified and biuret allophanate modified toluene diisocyanates, prepolymers thereof, and processes for their preparation KYAT1, KYNU, TDO2 CRBN 1622/4885LMNA 427/4885TSHR 3724/4885
US-20080262261-A1 STABLE LIQUID BIURET MODIFIED AND BIURET ALLOPHANATE MODIFIED TOLUENE DIISOCYANATES, PREPOLYMERS THEREOF, AND PROCESSES FOR THEIR PREPARATION KYAT1, KYNU, TDO2 CRBN 1622/4885LMNA 427/4885TSHR 3724/4885
US-20050020765-A1 Stable liquid biuret modified and biuret allophanate modified toluene diisocyanates, prepolymers thereof, and processes for their preparation KYAT1, KYNU, TDO2 CRBN 1622/4885LMNA 427/4885TSHR 3724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.