Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554882 | 0.86 | LMNA (0.42) | CYP1A2CYP2D6KMT2AACACBL3MBTL1 | |
| SCHEMBL30723841 | 0.81 | MAPT (0.57) | PROKR1MAPTKMT2ANPSR1KDM4E | |
| SCHEMBL1992514 | 0.81 | MAPT (0.57) | PROKR1MAPTKMT2ANPSR1KDM4E | |
| SCHEMBL14480077 | 0.81 | CREBBP (0.50) | PROKR1MAPTKMT2ANPSR1ACACB | |
| SCHEMBL7437293 | 0.80 | PROKR1 (0.48) | PROKR1MAPTCYP1A1CYP1A2CYP2D6 | |
| SCHEMBL30281260 | 0.80 | PARP10 (0.51) | PROKR1MAPTKMT2ANPSR1ACACB | |
| SCHEMBL6241029 | 0.80 | PARP10 (0.51) | PROKR1MAPTKMT2ANPSR1ACACB | |
| SCHEMBL17478456 | 0.80 | MAPT (0.56) | PROKR1MAPTKMT2ANPSR1KDM4E | |
| SCHEMBL3723629 | 0.79 | JMJD6 (0.56) | CYP1A2 | |
| SCHEMBL29173821 | 0.79 | KDM4E (0.55) | PROKR1MAPTACACBKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1201789-A | Pyridine-3,4-diketone derivatives and their preparation and medicinal uses | UNIV ZHONGSHAN (CN) | 1998-12-16 | — | — | CN | claimed |