Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARD | Q03181 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533198 | 0.86 | HDAC3 (0.53) | ALDH1A1NPC1RAB9APPARGPPARD | |
| SCHEMBL9718973 | 0.74 | MEN1 (0.81) | ALDH1A1SMN1; SMN2GLAMEN1NPC1 | |
| SCHEMBL29834246 | 0.71 | MEN1 (0.75) | ALDH1A1SMN1; SMN2GLAMEN1NPC1 | |
| SCHEMBL124894 | 0.71 | MEN1 (0.75) | ALDH1A1SMN1; SMN2GLAMEN1NPC1 | |
| SCHEMBL27887307 | 0.70 | TUBB4A (0.70) | ALDH1A1SMN1; SMN2GLAMEN1KMT2A | |
| SCHEMBL12405825 | 0.70 | MEN1 (0.72) | ALDH1A1SMN1; SMN2GLAMEN1NPC1 | |
| SCHEMBL314267 | 0.70 | ALDH1A1 (0.93) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9066312 | 0.70 | ALDH1A1 (0.93) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8471293 | 0.68 | KDM4E (0.68) | ALDH1A1SMN1; SMN2GLAMEN1NPC1 | |
| SCHEMBL135162 | 0.68 | ATM (1.00) | ALDH1A1SMN1; SMN2MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051313-C | 5-arylindole derivatives | PFIZER (US) | 2000-04-12 | — | — | CN | disclosed |
| CN-1094727-A | The 5-(hetero) aryl indole derivatives | PFIZER (US) | 1994-11-09 | — | — | CN | disclosed |