Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 11/20 | 0.35 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29896303 | 0.98 | CCR5 (0.34) | CCR5CCR2 | |
| SCHEMBL27408627 | 0.86 | FKBP5 (0.33) | FKBP5CRBN | |
| Hydrochloric Acid SCHEMBL27710822 | 0.76 | FKBP5 (0.34) | FKBP5CRBN | |
| SCHEMBL27820083 | 0.74 | TSHR (0.30) | TSHRNFKB1NFKB2RELA | |
| SCHEMBL3974402 | 0.71 | — | — | |
| SCHEMBL13837363 | 0.71 | TSHR (0.37) | CCR5TSHRNFKB1NFKB2RELA | |
| SCHEMBL8680264 | 0.70 | TSHR (0.36) | CCR5TSHRNFKB1NFKB2RELA | |
| SCHEMBL2180217 | 0.70 | TSHR (0.41) | CCR5TSHR | |
| SCHEMBL9062253 | 0.68 | CCR5 (0.40) | CCR5TSHR | |
| SCHEMBL11229187 | 0.68 | CCR5 (0.40) | CCR5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046278-C | Azolylamine derivative | KAKEN PHARMA CO LTD (JP) | 1999-11-10 | — | — | CN | disclosed |
| CN-1122598-A | Azolylamine derivative | KAKEN PHARMA CO LTD (JP) | 1996-05-15 | — | — | CN | disclosed |