Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27520753 | 0.85 | LMNA (0.38) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL27504115 | 0.84 | LMNA (0.37) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL27469808 | 0.83 | KMT2A (0.36) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL27485476 | 0.82 | NCEH1 (0.39) | CLCN2LMNAMAPTNPC1CASP3 | |
| SCHEMBL27499442 | 0.80 | FGFR1 (0.37) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL5486246 | 0.76 | NPC1 (0.45) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL27529112 | 0.76 | MAPT (0.45) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL27528720 | 0.75 | FGFR1 (0.38) | LMNAMAPTNPC1CASP3SENP8 | |
| SCHEMBL27501931 | 0.73 | PDCD1 (0.41) | ALDH1A1PTGDR2KDM4ENPSR1 | |
| SCHEMBL248601 | 0.72 | SMN1; SMN2 (0.44) | LMNAMAPTEGFRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1199954-C | Benzodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 2005-05-04 | — | — | CN | disclosed |
| CN-1379764-A | Benzodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 2002-11-13 | — | — | CN | disclosed |