Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428542 | 0.76 | ALDH1A1 (0.38) | HTR1AHTR7MEN1KMT2ALMNA | |
| SCHEMBL4416262 | 0.76 | HTR1A (0.38) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL4423588 | 0.75 | ESR1 (0.42) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL4417230 | 0.75 | HTR1A (0.38) | HTR1AHTR7MAPTLMNAMMP2 | |
| SCHEMBL4425309 | 0.73 | HTR1A (0.42) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL4417265 | 0.73 | MEN1 (0.43) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL3301404 | 0.71 | MALT1 (0.44) | ALDH1A1 | |
| SCHEMBL4430300 | 0.71 | HTR1A (0.41) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL4417932 | 0.71 | ESR1 (0.47) | HTR1AHTR7MEN1KMT2AMAPT | |
| SCHEMBL5009446 | 0.71 | HTR1A (0.72) | HTR1AHTR7KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1246323-C | Nitrogen-based camptothecin derivatives | CALIFORNIA PACIFIC MED CENTER (US) | 2006-03-22 | — | — | CN | disclosed |