Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7938719 | 0.91 | SLC6A3 (0.33) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL27522516 | 0.78 | SLC6A3 (0.38) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7938840 | 0.77 | BRD4 (0.37) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7935531 | 0.74 | SLC6A3 (0.35) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7935497 | 0.73 | SLC6A3 (0.35) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7935536 | 0.72 | SLC6A3 (0.36) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7744091 | 0.72 | SLC6A3 (0.36) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7938977 | 0.72 | SLC6A3 (0.36) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7936662 | 0.71 | SLC6A3 (0.33) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 | |
| Hydrochloric Acid SCHEMBL7933251 | 0.71 | SLC6A3 (0.33) | SLC6A3PTPN1NISCHALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1274359-A | Mu-oxometallocene complex compound, and olefin polymerization catalyst and polymerization method using same | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1274360-A | Processes for prepn. of metallocene complexes | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |