Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532760 | 0.93 | EPHX1 (0.58) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL11525493 | 0.93 | EPHX1 (0.58) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL6946859 | 0.93 | DGKA (0.56) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL8973569 | 0.93 | EPHX1 (0.58) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL11531047 | 0.93 | EPHX1 (0.58) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL11522408 | 0.93 | EPHX1 (0.58) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL6223307 | 0.91 | DGKA (0.53) | DGKAEPHX1DNM1PAMPRSS1 | |
| SCHEMBL29137394 | 0.88 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL11527233 | 0.88 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 | |
| SCHEMBL11525202 | 0.88 | DGKA (0.53) | DGKADNM1PAMPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379404-C | Liposome composition for reduction of liposome-induced complement activation | ALZA COPORATION (US) | 2008-04-09 | — | — | CN | disclosed |
| CN-1756534-A | Liposome composition for reduction of liposome-induced complement activation | ALZA COPORATION (US) | 2006-04-05 | — | — | CN | disclosed |
| CN-1193059-C | Neutral lipopolymer and liposome composition containing same | ALZA CORP (US) | 2005-03-16 | — | — | CN | disclosed |
| CN-1360611-A | Neutral lipopolymer and liposomal compositions contg. same | ALZA CORP (US) | 2002-07-24 | — | — | CN | disclosed |