SCHEMBL27525762

SCHEMBL27525762

Oc1cc(C(F)(F)F)ccc1C1CCCCC1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.51
CHRNB2 P17787 2/20 0.44
CHRNA4 P43681 2/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
PNMT P11086 1/20 0.44
HTR2A P28223 1/20 0.43
PTPN5 P54829 3/20 0.41
PTPN2 P17706 1/20 0.41
EPHX2 P34913 1/20 0.40
SLC6A9 P48067 1/20 0.40
NUDT1 P36639 1/20 0.40
BACE1 P56817 1/20 0.40
HSP90AA1 P07900 1/20 0.40
KDM1A O60341 1/20 0.39
KCNH2 Q12809 1/20 0.39
NLRP3 Q96P20 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1660877 0.91 CHRNB2 (0.47) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL27688013 0.86 PTGDR2 (0.55) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL9861406 0.84 PTGDR2 (0.52) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL17141453 0.77 CHRNB2 (0.47) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL18700726 0.76 CHRNB2 (0.49) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL25027142 0.76 PTGDR2 (0.51) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL3408785 0.76 PTGDR2 (0.51) PTGDR2CHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL19892266 0.76 ALDH1A1 (0.46) CHRNB2CHRNA4NUDT1BACE1HSP90AA1
SCHEMBL31545836 0.76 ALDH1A1 (0.46) CHRNB2CHRNA4NUDT1BACE1HSP90AA1
SCHEMBL30394481 0.76 ALDH1A1 (0.46) CHRNB2CHRNA4NUDT1BACE1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1219774-C Non-sterioid inflammation-resisting compound WANG SHUYUE (CN) 2005-09-21 CN disclosed
CN-1535961-A Non-sterioid inflammation-resisting compound 王淑月 2004-10-13 CN disclosed