SCHEMBL275286

SCHEMBL275286

C(=C/c1ccc(-n2c3ccccc3c3ccccc32)cc1)\c1ccc(N(c2ccccc2)c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
L3MBTL1 Q9Y468 3/20 0.53
ATM Q13315 2/20 0.53
APP P05067 1/20 0.45
RELA Q04206 1/20 0.41
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
POLB P06746 1/20 0.39
KLK7 P49862 1/20 0.39
HDAC4 P56524 1/20 0.37
MAPT P10636 5/20 0.36
ALDH1A1 P00352 4/20 0.36
TDP1 Q9NUW8 2/20 0.36
USP2 O75604 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TLR9 Q9NR96 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373027 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL36943 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL263082 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL36944 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL276794 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL260506 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL260507 0.98 KDM4E (0.52) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL23616149 0.94 L3MBTL1 (0.47) KDM4EL3MBTL1ATMAPPRELA
SCHEMBL12163946 0.93 MEN1 (0.49) KDM4EL3MBTL1ATMAPPMEN1
SCHEMBL10123774 0.93 KDM4E (0.46) KDM4EL3MBTL1ATMAPPRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-08-14 US disclosed
US-8704215-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-04-22 US disclosed
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-07-05 US disclosed
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-07-05 US disclosed
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-07-05 US disclosed
US-8134148-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-03-13 US disclosed
US-20100301322-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-12-02 US disclosed
US-20100301322-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-12-02 US disclosed
US-20100301322-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-12-02 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-7732619-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-06-08 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 KDM4E 3249/4885L3MBTL1 2886/4885ATM 2454/4885
US-20140225097-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 KDM4E 3249/4885L3MBTL1 2886/4885ATM 2454/4885
US-20120168741-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 KDM4E 3249/4885L3MBTL1 2886/4885ATM 2454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.