Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzoin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | CES2 | O00748 | 2/20 | 0.66 |
| ▸ | CES1 | P23141 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoin SCHEMBL27504403 | 0.94 | LMNA (0.75) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL25826 | 0.94 | LMNA (0.75) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL27283150 | 0.92 | LMNA (0.72) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL11570177 | 0.91 | LMNA (0.62) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL923010 | 0.91 | LMNA (0.62) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL22499691 | 0.90 | LMNA (0.70) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL604169 | 0.90 | LMNA (0.81) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL27526077 | 0.89 | LMNA (0.72) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL10336419 | 0.88 | LMNA (0.58) | LMNACES2CES1ALDH1A1KDM4E | |
| Benzoin SCHEMBL6261151 | 0.88 | LMNA (0.58) | LMNACES2CES1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1056856-C | High-temp. resistance and antisalt water-soluble optical polymer | INST OF PHOTOGRAPHIC CHEMISTRY (CN) | 2000-09-27 | — | — | CN | disclosed |