Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.79 |
| ▸ | PPARG | P37231 | 10/20 | 0.79 |
| ▸ | PPARD | Q03181 | 7/20 | 0.79 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.56 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.56 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.56 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.56 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.56 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742676 | 0.88 | PPARA (1.00) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL5147335 | 0.88 | PPARA (1.00) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL29557298 | 0.88 | PPARA (1.00) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6376945 | 0.86 | PPARA (0.86) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL6375543 | 0.86 | PPARA (0.86) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL5469444 | 0.84 | PPARA (0.73) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL5111743 | 0.82 | PPARA (0.89) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL5188840 | 0.81 | PPARA (0.86) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL5112917 | 0.80 | PPARA (0.84) | PPARAPPARGPPARDPSEN1PSEN2 | |
| SCHEMBL31861 | 0.80 | PPARD (0.64) | PPARAPPARGPPARDPTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648038-B2 | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments | SANOFI (FR) | 2014-02-11 | — | — | US | disclosed |
| US-8648038-B2 | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments | SANOFI (FR) | 2014-02-11 | — | — | US | disclosed |
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | SANOFI (FR) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004167-A1 | (2-ARYLOXYACETYLAMINO) PHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF AS MEDICAMENTS | GPR119, DPP9, DPP7 | PPARA 10/4885PPARG 44/4885PPARD 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.