Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.64 |
| ▸ | PPARA | Q07869 | 4/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.52 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13954715 | 0.85 | PTGER4 (0.73) | PPARDPPARAPPARGPTGER4PTGER2 | |
| SCHEMBL5974242 | 0.82 | PSEN1 (0.73) | PPARDPPARAPPARGPTPN7DUSP3 | |
| SCHEMBL31930 | 0.80 | MAPT (0.55) | PPARDPPARAPPARGPTGER4PTGER2 | |
| SCHEMBL2752926 | 0.80 | PPARA (0.79) | PPARDPPARAPPARGPTGER4PTGER2 | |
| SCHEMBL12635851 | 0.80 | HDAC3 (0.54) | PPARDPPARAPPARGPTPN7DUSP3 | |
| SCHEMBL31960 | 0.79 | PPARA (0.63) | PPARDPPARAPPARGPTGER4PTGER2 | |
| SCHEMBL6940681 | 0.79 | ALDH1A1 (0.54) | POLBKMT2APDE10A | |
| SCHEMBL5147335 | 0.79 | PPARA (1.00) | PPARDPPARAPPARGPSEN1PSEN2 | |
| SCHEMBL5469444 | 0.79 | PPARA (0.73) | PPARDPPARAPPARGPTGER4PTGER2 | |
| SCHEMBL2742676 | 0.79 | PPARA (1.00) | PPARDPPARAPPARGPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |