Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068594 | 0.91 | TSHR (0.54) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL23120125 | 0.91 | TSHR (0.46) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL5448469 | 0.90 | TSHR (0.47) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| Acrylic Acid Methyl Ester SCHEMBL4453899 | 0.88 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| Acrylic Acid SCHEMBL27810281 | 0.88 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| Methacrylic Acid SCHEMBL27531007 | 0.88 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL5080728 | 0.88 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL424597 | 0.88 | TSHR (0.44) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL27810283 | 0.87 | TSHR (0.49) | TSHRHPGDTHRBALDH1A1CYP3A4 | |
| SCHEMBL5971626 | 0.87 | TSHR (0.58) | TSHRHPGDTHRBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7580193-B2 | Plastic optical components and an optical unit using the same | FUJIFILM CORPORATION (JP) | 2009-08-25 | — | — | US | disclosed |
| US-20060056036-A1 | Plastic optical components and an optical unit using the same | FUJI PHOTO FILM CO., LTD. | 2006-03-16 | — | — | US | disclosed |