SCHEMBL27532012

SCHEMBL27532012

CCOC(=O)c1cc[c]c(CO)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
HSD17B2 P37059 1/20 0.45
CYP1A2 P05177 3/20 0.45
LMNA P02545 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAOA P21397 1/20 0.45
RAB9A P51151 4/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
NPC1 O15118 3/20 0.44
CYP2C9 P11712 2/20 0.44
HPGD P15428 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27287168 0.86 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL8772774 0.82 ALDH1A1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL7492169 0.81 CA12 (0.54) CA12CA1CA2CA7CA9
SCHEMBL6136451 0.81 NPC1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL128776 0.80 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL9658861 0.80 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL17688358 0.79 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL971745 0.79 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL3149483 0.79 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL9667627 0.78 PKM (0.46) LMNARAB9ASMN1; SMN2NPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100338051-C Process for the preparation of citalopram LUNDHECK AS H (DK) 2007-09-19 CN disclosed
CN-1286688-A Process for the preparation of citalopram LUNDHECK AS H (DK) 2001-03-07 CN disclosed