Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346563 | 0.72 | CA2 (0.41) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL7883065 | 0.69 | MAPT (0.52) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL623143 | 0.67 | MAPT (0.41) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL1639992 | 0.66 | MAPT (0.48) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL2644762 | 0.64 | MAPT (0.42) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL17294198 | 0.64 | MAPT (0.46) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL4629140 | 0.63 | PTPN1 (0.45) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11561272 | 0.63 | MAPT (0.41) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL472475 | 0.63 | MAPT (0.50) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL8738128 | 0.61 | MAPT (0.54) | MAPTLMNATP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1319929-C | Aryl phenyl substituted cyclic ketoenols | BAYER AG (DE) | 2007-06-06 | — | — | CN | disclosed |
| CN-1286809-C | Arylphenyl-substituted cyclic ketoenols | BAYER AG (DE) | 2006-11-29 | — | — | CN | disclosed |
| CN-1206218-C | Aryl phenyl substituted cyclic ketoenols | BAYER AG (DE) | 2005-06-15 | — | — | CN | disclosed |
| CN-1600772-A | Aryl phenyl substituted cyclic ketoenols | BAYER AG (DE) | 2005-03-30 | — | — | CN | disclosed |
| CN-1590372-A | Arylphenyl-substituted cyclic ketoenols | BAYER AG (DE) | 2005-03-09 | — | — | CN | disclosed |
| CN-1303375-A | Aryl phenyl substituted cyclic ketoenols | BAYER AG (DE) | 2001-07-11 | — | — | CN | disclosed |