SCHEMBL27533432

SCHEMBL27533432

CC(=O)Nc1ccc(C(=O)Oc2ccccc2)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.73
KDM4E B2RXH2 5/20 0.73
MAPK1 P28482 3/20 0.73
HPGD P15428 6/20 0.70
HSD17B10 Q99714 5/20 0.70
RAB9A P51151 2/20 0.70
ALOX15 P16050 2/20 0.70
CYP1A2 P05177 1/20 0.70
CYP2D6 P10635 1/20 0.70
CYP2C9 P11712 1/20 0.70
CYP2C19 P33261 1/20 0.70
CASP3 P42574 1/20 0.70
SENP8 Q96LD8 1/20 0.70
SENP7 Q9BQF6 1/20 0.70
SENP6 Q9GZR1 1/20 0.70
SMN1; SMN2 Q16637 3/20 0.68
ALDH1A1 P00352 5/20 0.64
GAA P10253 2/20 0.64
NPC1 O15118 1/20 0.64
LMNA P02545 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27603205 0.99 MAPT (0.71) MAPTKDM4EMAPK1HPGDHSD17B10
Phenyl Aminosalicylate SCHEMBL3310602 0.87 MAPT (0.73) MAPTKDM4EMAPK1HPGDHSD17B10
SCHEMBL2351470 0.87 MAPT (0.67) MAPTKDM4EMAPK1HPGDHSD17B10
SCHEMBL7085631 0.84 HPGD (0.57) MAPTKDM4EMAPK1HPGDHSD17B10
SCHEMBL7199427 0.83 MAPT (0.70) MAPTKDM4EMAPK1HPGDHSD17B10
SCHEMBL7199385 0.83 HSD17B10 (0.56) MAPTKDM4EMAPK1HPGDHSD17B10
Acetaminosalol SCHEMBL5083330 0.83 HPGD (0.94) MAPTKDM4EMAPK1HPGDHSD17B10
SCHEMBL7088771 0.83 GAA (0.62) MAPTKDM4EMAPK1HPGDHSD17B10
Acetaminosalol SCHEMBL30383652 0.82 HPGD (1.00) MAPTKDM4EHPGDHSD17B10RAB9A
Acetaminosalol SCHEMBL25220 0.82 HPGD (1.00) MAPTKDM4EHPGDHSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1254731-A Latent thiol stabilizer for improving ageing nature of transparent composition containing helogen polymer MORTON INT INC (US) 2000-05-31 CN disclosed